Does Dexmedetomidine Reduce Delirium by Improving Sleep?
نویسندگان
چکیده
Delirium is a common complication in intensive care unit (ICU) patients and its occurrence is associated with worse outcome (Inouye et al. 2014; Abelha et al. 2013). Sleep disturbances are considered one of the important risk factors of delirium development (Flink et al. 2012). Recent evidence shows that dexmedetomidine, either at sedative or non-sedative doses, can improve sleep quality and reduce delirium. Here we review evidence regarding sleep disturbances, delirium, and the effects of dexmedetomidine in ICU patients.
منابع مشابه
'From darkness into light': time to make awake intubation with videolaryngoscopy the primary technique for an anticipated difficult airway?
Effect of ketamine versus alfentanil following midazolam in preventing emergence agitation in children after sevoflurane anaesthesia: A prospective random-ized clinical trial. Ketamine is effective in decreasing the incidence of emergence agitation in children undergoing dental repair under sevo-flurane general anesthesia. Effects of ketamine and midazolam on emergence agitation after sevoflura...
متن کاملDefining the Role of Dexmedetomidine in the Prevention of Delirium in the Intensive Care Unit
Dexmedetomidine is a highly selective α 2 agonist used as a sedative agent. It also provides anxiolysis and sympatholysis without significant respiratory compromise or delirium. We conducted a systematic review to examine whether sedation of patients in the intensive care unit (ICU) with dexmedetomidine was associated with a lower incidence of delirium as compared to other nondexmedetomidine se...
متن کاملUse of dexmedetomidine for primary sedation in a general intensive care unit.
romotion of rest and sleep in critically ill patients facilitates healing. Multisystem adverse effects of sleep deprivation have been reported. Physical activity also plays a pivotal role in recovery and long-term outcomes. Use of sedation is important to help achieve the right balance between sleep and wakefulness; the correct balance is essential for incorporating physical activity and patien...
متن کاملUpdate on Sedation in the Critical Care Unit
Recognition and treatment of pain, agitation and anxiety is a challenge in the care of Intensive Care Unit (ICU) patients. Management of pain, agitation and anxiety is necessary for patient comfort, and reduces long term psychological sequelae of ICU admission, time on mechanical ventilation, and length of stay in both the ICU and hospital. ICU providers must be very familiar with the pharmacol...
متن کاملAltering intensive care sedation paradigms to improve patient outcomes.
Providing sedation and comfort for intensive care patients has evolved in the last few years. New approaches to improving outcomes for intensive care unit (ICU) patients include providing analgesia before adding sedation and recognizing dangerous adverse effects associated with sedative medications, such as prolonged effects of midazolam, propylene glycol toxicity with lorazepam, propofol infus...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017